Empagliflozin Nruab Nrab

Empagliflozin Nruab Nrab

Acetyl Empagliflozin (Cas # 915095- 99- 7)
Iodinated empagliflozin intermediate (CAS # 915095- 94- 2)
Brominated empagliflozin intermediate (CAS # 915095- 89- 5)

Dawb rau off-dawb crystalline hmoov

Purity ntau dua lossis sib npaug rau 98. 0% (los ntawm HPLC)

Empagliflozin yog ib tug xaiv siab sodium-glupose co-transpor {2}} (sglt2) inhibitor qhia rau kev tswj hwm ntawm ob peb tus mob chronic:

Hom 2 Ntshav Qab Zib Mellitus:
Empagliflozin tswj glycemic tswj nyob rau hauv cov neeg laus uas muaj cov kab mob ntshav qab zib hom 2 nyob rau hauv lub proximal reabtoorption thiab nce kev tso zis rau kev ua kom muaj kev phom sij.
Nws yog siv:
Raws li monotherapy thaum Metformin tsis tsim nyog vim yog tsis muaj kev xav lossis cov contraindications.
Ua ib feem ntawm kev kho cua nrog lwm cov tshuaj pleev ib ce (xws li manformicin, dpp {{} {}}) kom ua tiav cov ntshav ntshav qab zib ntshav qab zib.
Txhawm rau muab cov txiaj ntsig kev pab them nyiaj ntxiv dhau ntawm kev tswj hwm glyolemic.

Lub plawv tsis ua hauj lwm nrog txo qhov kev ntsuas feem (HFF):
Empagliflozin ho txo ​​qhov kev pheej hmoo ntawm kev pheej hmoo ntawm plawv kev tuag thiab kev kho mob rau lub plawv tsis ua tiav ntawm tus mob ntshav qab zib.
Cov chaw kuaj mob (xws li tus neeg sawv cev ntawm huab tais (xws li emperor-txo) tau pom dua cov txiaj ntsig hauv lub neej no thiab morbidity ntawm cov neeg mob kho nrog empagliflozin.

Ntev raum mob raum (CKD):
Empagliflozin kuj tau qhia kom qeeb ntawm kab mob raum, txo qhov kev pheej hmoo ntawm mob raum, thiab txo tus kab mob plawv mob raum, thiab txo tus kab mob plawv mob raum, thiab txo cov kab mob plawv mob
Nws ua qauv qhia cov calal tiv thaiv cov teebmeem ywj pheej ntawm kev tswj hwm glycemic.

Txo Kev Nyab Xeeb Kev Nyab Xeeb:
Hauv cov neeg mob uas muaj hom ntshav qab zib hom 2 thiab tsim cov kab mob plawv, thiab tsis muaj kev pheej hmoo ntawm cov kev pheej hmoo ntawm Empa, raws li tau pom tseeb hauv EMPA-Rege tshwm sim kev sim.

Mechanism ntawm Kev Ua:
Los ntawm kev txo cov ntshav ntshav ntshav ntshav ntshav qab zib ntawm nws txoj kev insulin uas muaj kev pheej hmoo ntawm hypoglycemia thiab ua rau muaj kev txo qis thiab coj ntshav siab txo.

Conforms rau USP thiab EP.

Khaws ntawm - 20 degree lossis hauv qab hauv lub thawv kaw nruj.
Tiv thaiv los ntawm cov dej noo, lub teeb, thiab kub siab.
Tswj hwm hauv qab cov pa roj av yog tias tsim nyog.

Cim npe nrov: Empagliflozin Nruab Nrab, Tuam Tshoj Empagliflozin Intermediat Cov Chaw Tsim Tshuaj, Cov Chaw Muag Khoom